As the first standalone sequel for Doctor Strange (Benedict Cumberbatch), Multiverse of Madness follows the Sorcerer Supreme as he tries to contain the aftermath of the multiverse-fracturing spell he cast in Spider-Man: No Way Home – which caused villains from across the multiverse to spill over into the central Marvel Cinematic Universe timeline. The film is also set after the events of WandaVision and Loki, and Doctor Strange teams up with Wanda Maximoff (Olsen).
In the first trailer for Multiverse of Madness, which was originally released as a post-credits scene for No Way Home last December, viewers caught a glimpse of the Doctor Strange-Wanda meet-up, action-packed battle scenes and someone who appears to be an evil, alternate version of Doctor Strange, who originally appeared in the animated Disney Plus series What If...?.