In 2013, American actress Angelina Jolie, who has never had cancer before, decided to have a preventive double mastectomy because she has a BRCA1 gene mutation, which puts her at increased risk (87%) of developing breast cancer. And, in 2015, she had her ovaries and fallopian tubes removed to reduce her risk of developing ovarian cancer, the disease that killed her mother at the age of just 56.
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