You never know what lies around you, and in this case, it turned out to be a possible cancer-fighting candidate living in goose poop! — TNS
Many researchers can go their entire careers, and sometimes their entire lives, without making a groundbreaking discovery.
They might contribute to a body of research, or dive deeper into a topic, but many may not make waves in their fields until much later in their careers, or maybe not at all.
This isn’t the case for Camarria Williams.
The American middle-schooler is a member of the Boys and Girls Club, and was recruited by the University of Illinois at Chicago to be part of a 14-week science programme for young people to learn about scientific careers, according to an Oct 24 (2024) study and Dec 2 (2024) news release from the American Chemical Society (ACS).
Williams and the other students were tasked with bringing in things from their environment to the Chicago Antibiotic Discovery Lab.
The researchers there work on discovering new sources for antibiotics in the world around us.
Williams’ contribution was goose poop collected from around Garfield Park Lagoon in the city of Chicago, according to the study.
The sample was placed on an agar plate (the medium for anything alive in the poop to grow), then under a microscope.
The students “stayed actively involved throughout the scientific discovery process by programming a specialised robot to scoop up bacterial colonies from growth plates and test them for antibiotic activity”, according to the ACS.
Inside the goose poop, the researchers found a bacteria from the strain Pseudomonas idahoensis, a group known to have disease-fighting properties, according to a July 10 (2024) news release from the Illinois-Indiana Sea Grant, which funds the project.
“We identified some compounds to be cyclic peptides, which are famous for having biologic activity,” programme leader and medicinal chemist Professor Dr Brian Murphy said in July (2024).
“Amazingly, it turns out these particular compounds don’t have antibiotic activity, but they do have cytotoxic activity – activity against some cancer cell lines.”
The newly-discovered bacterium was tested against human melanoma cells and human ovarian cancer cells, and the researchers found that the growth of the cancer cells slowed when exposed to the goose-poop bacteria.
There are many steps between the bacteria appearing in goose poop and it becoming a cancer treatment, but Williams can now add “study author” to her list of accomplishments before even starting high (secondary) school.
“I think the most rewarding part for me is seeing the progress as kids became more confident in themselves over time,” lab researcher and PhD candidate Tan Jin Yi said in July (2024).
“Like, yeah, I can programme stuff. I can do this. I chose these samples.” – By Irene Wright/The Charlotte Observer/Tribune News Service
