Study traces common brain malformation to genetic roots


By Xu Jing
  • World
  • Wednesday, 30 Dec 2020

CHICAGO, Dec. 29 (Xinhua) -- Researchers at Washington University School of Medicine in St. Louis have shown in a study that Chiari 1 malformation, a common brain disorder, can be caused by variations in two genes involved in brain development.

To identify genes that cause Chiari 1 malformation, the researchers sequenced all the genes of 668 people with the condition, as well as 232 of their relatives. Of these relatives, 76 also had Chiari 1 malformation and 156 were unaffected.

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